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Table 3 Association between dietary total vitamin B2 intake and femoral BMD

From: Dietary riboflavin (vitamin B2) intake and osteoporosis in U.S. female adults: unveiling of association and exploration of potential molecular mechanisms

Characteristics

Model 1

β (95%CI) P-value

Model 2

β (95%CI) P-value

Model 3

β (95%CI) P-value

Total femur BMD

Vitamin B2

0.004 (-0.000, 0.009) 0.062

0.006 (0.002, 0.010) 0.004

0.008 (0.003, 0.012) 0.001

Vitamin B2 quartile

 Q1

Reference

Reference

Reference

 Q2

-0.003 (-0.014, 0.009) 0.625

0.009 (-0.001, 0.019) 0.080

0.006 (-0.004, 0.015) 0.242

 Q3

0.002 (-0.009, 0.014) 0.688

0.014 (0.003, 0.025) 0.011

0.010 (-0.000, 0.021) 0.061

 Q4

0.014 (0.001, 0.028) 0.037

0.019 (0.007, 0.031) 0.002

0.020 (0.007, 0.033) 0.002

P for trend

0.051

0.001

0.017

Femoral neck BMD

Vitamin B2

0.002 (-0.003, 0.006) 0.430

0.004 (0.000, 0.008) 0.046

0.005 (0.001, 0.009) 0.017

Vitamin B2 quartile

 Q1

Reference

Reference

Reference

 Q2

-0.009 (-0.020, 0.003) 0.135

0.008 (-0.002, 0.017) 0.119

0.005 (-0.004, 0.014) 0.289

 Q3

-0.003 (-0.015, 0.009) 0.658

0.013 (0.003, 0.023) 0.010

0.010 (-0.000, 0.020) 0.050

 Q4

0.007 (-0.007, 0.021) 0.317

0.013 (0.002, 0.025) 0.025

0.015 (0.002, 0.027) 0.022

P for trend

0.394

0.007

0.041

Trochanter BMD

Vitamin B2

0.005 (0.001, 0.009) 0.007

0.006 (0.002, 0.009) 0.001

0.007 (0.003, 0.011) 0.001

Vitamin B2 quartile

 Q1

Reference

Reference

Reference

 Q2

0.002 (-0.007, 0.011) 0.675

0.010 (0.001, 0.019) 0.025

0.007 (-0.001, 0.015) 0.090

 Q3

0.004 (-0.006, 0.013) 0.457

0.011 (0.001, 0.020) 0.023

0.007 (-0.002, 0.017) 0.116

 Q4

0.018 (0.007, 0.029) 0.001

0.019 (0.009, 0.030) 0.000

0.020 (0.009, 0.031) 0.000

P for trend

0.126

0.009

0.008

Intertrochanter BMD

 

Vitamin B2

0.004 (-0.001, 0.010) 0.126

0.007 (0.002, 0.011) 0.009

0.009 (0.003, 0.014) 0.001

Vitamin B2 quartile

 Q1

Reference

Reference

Reference

 Q2

-0.004 (-0.017, 0.010) 0.567

0.009 (-0.003, 0.021) 0.149

0.005 (-0.006, 0.017) 0.372

 Q3

0.002 (-0.012, 0.016) 0.807

0.015 (0.002, 0.028) 0.025

0.011 (-0.002, 0.023) 0.103

 Q4

0.013 (-0.003, 0.029) 0.101

0.020 (0.005, 0.035) 0.007

0.022 (0.006, 0.037) 0.007

P for trend

0.126

0.003

0.038

  1. Abbreviations: BMD, bone mineral density; BMI, body mass index; MET, metabolic equivalent task; PIR, ratio of family income to poverty; ALP, Alkaline phosphatase, OR, odds ratio; CI, confidence interval. Model 1, no covariates were adjusted. Model 2, demographic covariates were adjusted, including age, race, education, marital status, and PIR. Model 3, based on Model 2, was additionally adjusted for covariates of BMI, prednisone or cortisone intake, milk consumption, Vitamin D supplement, diabetes, smoking, menopause, total MET, serum albumin, serum ALP, serum total calcium, serum phosphorus, and energy intake
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Nutrition Journal

ISSN: 1475-2891

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