Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

You are viewing the site in preview mode

Skip to main content

Table 5 Changes from baseline in hematological parameters in the saffron and placebo groups

From: The effects of saffron supplementation on inflammation and hematological parameters in patients with sepsis: a randomized controlled trial

Variables

Group

Before intervention

After intervention

P-value**

Mean changes#

p-value

WBC (µL)

Saffron

13731.06 ± 3718.4

9554.71 ± 2961.91

<0.001

-4176.34 ± 4063.01

<0.001

Placebo

13499.43 ± 4790.74

13,561 ± 3316.32

0.92

61.57 ± 4118.97

P-value

0.79

<0.001

  

Cohen’s d effect size (95% CI)

0.05 (-0.36, 0.47)

-1.27 (-1.69, -0.86)

  

Neutrophils (%)

Saffron

74.31 ± 9.59

71.83 ± 15.22

0.34

-2.47 ± 17.37

0.48

Placebo

77.07 ± 8.43

74.13 ± 7.84

0.05

-2.93 ± 9.95

P-value

0.15

0.37

  

Cohen’s d effect size (95% CI)

-0.31 (-0.72, 0.11)

-0.19 (-0.61, 0.23)

  

Lymphocyte (%)

Saffron

17.19 ± 7.52

17.58.5.37

0.60

0.39 ± 5.09

0.21

Placebo

14.61 ± 5.82

15.33 ± 5

0.46

0.71 ± 6.46

P-value

0.07

0.04

  

Cohen’s d effect size (95% CI)

0.38 (-0.04, 0.8)

0.43 (0.01, 0.85)

  

RBC (µL)

Saffron

3.83 ± 0.61

3.75 ± 0.45

0.32

-0.080.54

0.18

Placebo

3.58 ± 0.34

3.54 ± 0.35

0.49

-0.03 ± 0.36

P-value

0.02

0.02

  

Cohen’s d effect size (95% CI)

0.51 (0.09, 0.93)

0.52 (0.1, 0.94)

  

Hb (g/dL)

Saffron

10.36 ± 1.49

10.24.1.58

0.62

-0.11 ± 1.55

0.19

Placebo

10.16 ± 1.42

9.81 ± 1.18

0.10

-0.34 ± 1.38

P-value

0.50

0.14

  

Cohen’s d effect size (95% CI)

0.14 (-0.28, 0.56)

0.31 (-0.11, 0.73)

  

Hct (%)

Saffron

31.44 ± 4.93

32.05 ± 4.87

0.37

0.60 ± 4.54

0.06

Placebo

30.79 ± 4.57

30.39 ± 2.66

0.56

-0.39 ± 4.55

P-value

0.51

0.04

  

Cohen’s d effect size (95% CI)

0.14 (-0.28, 0.56)

0.42 (0.00, 0.84)

  

MCV (fl.)

Saffron

84.48 ± 6.47

85.15 ± 5.74

0.25

0.66 ± 3.84

0.58

Placebo

85.06 ± 5.30

85.90 ± 4.39

0.10

0.84 ± 3.44

P-value

0.64

0.48

  

Cohen’s d effect size (95% CI)

-0.1 (-0.52, 0.32)

-0.15 (-0.57, 0.27)

  

MCH (pg)

Saffron

27.10 ± 2.65

26.97 ± 1.97

0.54

-0.12 ± 1.43

0.54

Placebo

27.01 ± 1.77

27.03 ± 1.65

0.86

0.02 ± 0.90

P-value

0.86

0.18

  

Cohen’s d effect size (95% CI)

0.04 (-0.38, 0.46)

-0.03 (-0.45, 0.39)

  

MCHC (g/dl)

Saffron

32.10 ± 1.81

31.66 ± 1.15

0.06

-0.43 ± 1.55

0.28

Placebo

31.67 ± 1.14

31.80 ± 1.42

0.60

0.12 ± 1.60

P-value

0.18

0.61

  

Cohen’s d effect size (95% CI)

0.28 (-0.13, 0.70)

-0.11 (-0.53, 0.31)

  

PLT (µL)

Saffron

278990.79 ± 130107.67

308031.36 ± 78889.79

0.11

29040.56 ± 120466.12

0.2

Placebo

243621.4 ± 112479.34

318532.10 ± 108062.43

<0.001

74910.70 ± 108276.04

P-value

0.17

0.60

  

Cohen’s d effect size (95% CI)

0.29 (-0.13, 0.71)

-0.11 (-0.53, 0.31)

  
  1. Abbreviations: WBC; white blood cell count, RBC; red blood cell, PLT; Platelet, Hb, hemoglobin; Hct, Hematocrit, CI: confidence interval
  2. Data are shown as means ± standard deviation
  3. *P-values were obtained from independent sample t-test, **paired-sample t-test, and #analysis of covariance (ANCOVA) with the adjustment for baseline values
Back to article page

Nutrition Journal

ISSN: 1475-2891

Contact us